Pal-GHK (Palmitoyl Tripeptide-1) (200mg)

$199.00

Pal-GHK is a synthetic lipopeptide combining a fatty acid with a messenger tripeptide. Researched for its ability to mimic collagen fragments, it acts as a biological signal to attract fibroblasts and stimulate the production of the skin’s extracellular matrix (ECM), including collagen and elastin.

Form: Lyophilized Powder
Primary Action: Collagen Fragment Mimetic (Signaling Peptide)
Research Focus: Wound healing, dermal structural integrity, and skin pigmentation.

SKU: Pal-GHK (Palmitoyl Tripeptide-1) (200mg) Category: Peptides

Pal-GHK (Palmitoyl Tripeptide-1) – The Collagen-Signaling Messenger Peptide

Pal-GHK, commonly known as Palmitoyl Tripeptide-1 or Palmitoyl Oligopeptide, is a synthetic hybrid molecule consisting of the tripeptide Glycine-Histidine-Lysine (GHK) covalently linked to palmitic acid. This “Pal” attachment is a critical research modification designed to enhance the peptide’s lipophilicity, allowing for superior penetration through the stratum corneum and into target skin cells.

Key Research Areas:

Extracellular Matrix (ECM) Support: Pal-GHK is a fragment of the alpha 2(I) chain of Type I Collagen. In research models, the presence of this specific sequence acts as a “false signal” of collagen degradation, triggering the body to initiate repair and synthesize new structural proteins.
Fibroblast Recruitment: Studies suggest that Pal-GHK serves as a powerful chemoattractant for fibroblasts. These cells are responsible for the synthesis of collagen, elastin, and other essential proteins in the skin, bones, and connective tissues.
Wound Healing Signaling: Researchers hypothesize that GHK sequences are naturally liberated by proteases at wound sites. By introducing synthetic Pal-GHK, scientists can study the acceleration of the natural repair response and the reinforcement of the dermal matrix.
Enhanced Bioavailability: The addition of the Palmitoyl group significantly improves the peptide’s ability to bypass the skin’s protective lipid barrier. This makes it an ideal model for investigating topical delivery systems and localized tissue remodeling.
Pigmentation & Skin Tone: Beyond structural repair, Pal-GHK is researched for its potential impact on skin pigmentation, exploring how the reinforcement of the ECM affects overall skin clarity and health.

Elite Peptide Supply provides high-purity Pal-GHK for advanced dermatological and tissue repair research. Our peptide is synthesized to ensure exact fatty-acid conjugation, providing a stable and effective tool for mapping collagen synthesis pathways.