GHK Basic Peptide | Glycyl-L-Histidyl-L-Lysine (NSC661251) | Elite Peptide Supply
GHK Basic is an endogenous tripeptide (Glycyl-L-Histidyl-L-Lysine) that serves as a vital molecular signal for tissue regeneration. Naturally synthesized in human plasma, its concentrations are known to decline with age, marking it as a primary subject for research into cellular longevity and restorative biochemistry.
This “free base” version of GHK is a critical fragment of the type I collagen chain and the SPARC protein. Researchers investigate GHK Basic for its ability to act as a “matrikine”—a peptide liberated during tissue injury that signals the body to initiate the healing process.
Key Research Mechanisms & Interests:
- Wound Healing Signaling: Studies suggest that GHK is released via hydrolysis at injury sites, where it may trigger fibroblasts to synthesize new collagen, elastin, and glycosaminoglycans.
- Extracellular Matrix (ECM) Regulation: Investigated for its role in regulating cell shape and proliferation through its interaction with the SPARC protein.
- Gene Modulation: Research indicates GHK may influence genes responsible for the anti-inflammatory response and recuperative pathways following oxidative stress.
- Angiogenesis & Nerve Growth: Experimental models explore its potential to stimulate blood vessel formation and nerve outgrowth during tissue remodeling.
- Systemic Potential: Beyond dermal repair, GHK is studied for potential nootropic (cognitive) effects and its role in pain perception inhibition.
Product Specifications:
- Amino Acid Sequence: Gly-His-Lys
- Molecular Formula: C14H24N6O4
- Molecular Weight: 340.4 g/mol
- Synonyms: NSC661251, Glycylhistidyllysine, GHK Free Base
- Purity: ≥99% (HPLC Verified)
- Format: Lyophilized powder for maximum stability.
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