The potential of mitochondrial communication with MOTS-c (Mitochondrial open-reading-frame of the 12S rRNA-c). This 16-amino acid bioactive peptide is a primary focus for researchers exploring the cutting edge of metabolic health and anti-aging science.
Initially thought to act solely within the mitochondria, recent data suggests MOTS-c functions as a systemic signaling molecule—a mitokine—circulating via the bloodstream to influence cellular environments far beyond its origin.
Key Research Areas for MOTS-c:
- Metabolic Efficiency: Studies focus on MOTS-c’s role in glucose metabolism and its potential as an “exercise mimetic” to improve insulin sensitivity.
- Longevity & Cell Function: Investigated for its ability to regulate nuclear gene expression in response to metabolic stress, potentially slowing age-related decline.
- Muscle Performance: Active research explores its influence on muscle contractile force and physical endurance.
- Weight Regulation: Emerging evidence highlights MOTS-c’s impact on metabolic flexibility and fat oxidation pathways.
Product Specifications:
- Amino Acid Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg
- Molecular Formula: C101H152N28O22S2
- Molecular Weight: 2174.64 g/mol
- Synonyms: 12S rRNA-c, MT-RNR1, Mitochondrial-Derived Peptide (MDP)
- Purity: ≥99% (HPLC Verified)
- Format: Lyophilized powder for laboratory stability.






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