Vialox Peptide (Pentapeptide-3V) | Nicotinic AChR Inhibitor | Elite Peptide Supply
Vialox (Pentapeptide-3V) is a specialized five-amino acid peptide derived from the molecular structure of endogenous snake venom. It is a primary subject in dermatological and neurological research due to its hypothesized ability to replicate localized muscular paralysis through a non-depolarizing mechanism.
The peptide’s function is often compared to tubocurarine (curare), a potent neurotoxin. By interacting with the postsynaptic membrane of muscle cells, Vialox is studied for its potential to block electrical impulses at the neuromuscular junction, effectively halting the trigger for muscle contraction.
Key Research Areas for Vialox:
- AChR Inhibition: Research focuses on Vialox’s ability to inhibit nicotinic acetylcholine receptors (nAChR), preventing the neurotransmitter acetylcholine from initiating muscle movement.
- Wrinkle Depth Reduction: Similar to botulinum toxin studies, researchers explore how temporary muscle immobilization can decrease the depth of existing skin creases and prevent new line formation.
- Neuromuscular Junction (NMJ) Dynamics: Used as a molecular model to study “curare-like” actions and the obstruction of nervous system electrical impulses in vitro.
- Topical Paralytic Mimicry: Investigated as a non-invasive alternative to traditional paralytic compounds for localized tissue relaxation.
Product Specifications:
- Amino Acid Sequence: Gly-Pro-Arg-Pro-Ala
- Molecular Formula: C21H37N9O5
- Molecular Weight: 495.58 g/mol
- PubChem CID: 67073230
- Synonyms: Pentapeptide-3V, Vialox Peptide
- Purity: ≥99% (HPLC Verified)
- Format: Lyophilized powder for laboratory stability.






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